Overview:
 
The CENTRII (The Center for Radiation Injury Intervention) website has been constructed to provide new and expanded education resources to improve expertise in radiobiology.  CENTRII is one of eight Centers for Medical Countermeasures Against Radiation (CMCR's) established by the RFA (Request for Application):

Centers for Medical Countermeasures Against Radiation
RFA (Request for Application) Number: RFA-AI-04-045 (Part I Overview Information)
http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-04-045.html

 
A set of links to the other CMCR's is available at the following webpage:
 

http://www3.niaid.nih.gov/topics/radnuc/funding/CMCRawardees.htm

 
The following excerpt gives an executive summary of the goals of the CMCR Project:

The primary goal of the Centers for Medical Countermeasures Against Radiation (CMCR) will be to develop new medical products that will protect against, mitigate the effects of, and treat the short- and long-term consequences of radiation exposure due to terrorist attack. NIAID intends to commit approximately $28 million in Fiscal Year 2005 to fund six to eight CMCRs as cooperative (U19) agreements.

 
CENTRII is dedicated to aid in supporting the educational aspects of this project and to provide a virtual campus for trainees located in Michigan, Wisconsin and Toronto, Canada.
 
In a broader sense the CENTRII website provides a virtual and centralized "campus" for the Education Core of the CMCR project.  CENTRII fulfills this role by providing a host of services:
 
* A "live" lecture series that allows virtual attendees to view the "live webcast" and ask questions from any location that has high speed internet capabilities.
* An archive of each lecture that can be viewed at the convenience of the user.
* Provide a Central Repository for Student Training Logs that are accessible to all Project Leaders.
 
The following table (below) provides an overview of the Center for Medical Countermeasures Against Radiation (CMCR) as presented at the Medical College of Wisconsin on Tuesday, February 28th, 2006, by John E. Moulder, Ph.D. (Professor of Radiation Oncology, Medical College of Wisconsin).  
 
Notes:
* Clicking on a "Topic" will launch a Power Point Presentation relating to the topic.
* Clicking on a "Abstract" will launch a link to the Crisp website's abstract information.
* Clicking on the "CRISP" button below the table will bring up the CRISP (Computer Retrieval of Information on Scientific Projects) database of federally funded biomedical research projects conducted at universities, hospitals, and other research institutions.  Type "%1U19AI067734%" into the "Grant number" box and then click on the “Submit Query” button at the bottom of the form.  [Note: Do not include the quotation marks in the query].  This will bring up the CRISP information on the CMCR grant.
 
 
Topic Abstract Speaker PI Name Grant Number
Introduction        
Overview of the Centers for Medical Countermeasures   C. Norman Coleman, M.D.    
Overview of the MCW-based Center Program   John E. Moulder, Ph.D.    
Projects        
Post-irradiation Modulation of Gastrointestinal Injury A Mary F. Otterson, M.D. Otterson, Mary 1U19AI067734-010001

Post-irradiation Intervention to Mitigate and Treat Chronic Renal Injuries

B Eric P. Cohen, M.D. Moulder, John 1U19AI067734-010002

Modulation of Post-irradiation Changes in Pulmonary Vasculature

C

Meetha M. Medhora, Ph.D.

 

MEDHORA, MEETHA 1U19AI067734-010003

Mitigating and Treating the Effects of Radiation on Lung Tissue

 

D

Richard P. Hill, Ph.D.

 

HILL, RICHARD 1U19AI067734-010004

Mitigating and Treating Radiation-induced CNS Injury with ACE Inhibitors and Statins

 

E

Jae Ho Kim, M.D., Ph.D.

 

KIM, JAE HO 1U19AI067734-010005
Scientific Cores        

Drug Discovery

1

Susan R. Doctrow, Ph.D.

DOCTROW, SUSAN 1U19AI067734-019004
Training and Education 2

Stephen Brown, Ph.D.

MOULDER, JOHN 1U19AI067734-019002
Irradiation 3 X. Allen Li, Ph.D. LI, X 1U19AI067734-019003
Pilot Research Projects 4 Robert L. Truitt, Ph.D. MOULDER, JOHN 1U19AI067734-019001 4

CRISP